PROGRAMME
last update August 28th, 2009
Last programme (.pdf)
Poster sessions (pdf)
WEDNESDAY, September 9th
THURSDAY, September 10th
FRIDAY, September 11th
SATURDAY, September 12th
last update August 28th, 2009
Last programme (.pdf) Poster sessions (pdf)WEDNESDAY, September 9th
| 15.00 - 18.00 |
Registration |
| 18.00 - 18.15 | RDPA 2009 welcome by Academic Authorities |
| 18.15 - 19.00 | Opening Plenary Lecture R&D , THE 'SILENT KILLER' OF THE OLD ORGANIZATIONAL MODEL OF PHARMA INDUSTRY M. Scatigna (Sanofi – Aventis, Milan, Italy) |
| 19.00 - 20.30 | Welcome cocktail |
THURSDAY, September 10th
9.00 - 9.40 |
Chairmen: C. Barbas (Spain), B. Chankvetadze (Georgia) Plenary lecture 1 THE APPLICATION OF BIOCHROMATOGRAPHY TO THE DISCOVERY OF NEW DRUGS FOR THE TREATMENT OF BRAIN CANCERS M. Sanghvi, R. Moaddel, I.W. Wainer (National Institute on Aging/NIH, Baltimore, U.S.A.) |
| 9.00 - 9.40 |
Plenary lecture 1 THE APPLICATION OF BIOCHROMATOGRAPHY TO THE DISCOVERY OF NEW DRUGS FOR THE TREATMENT OF BRAIN CANCERS M. Sanghvi, R. Moaddel, I.W. Wainer (National Institute on Aging/NIH, Baltimore, U.S.A.) |
| 9.40 - 10.10 | Key note lecture 1 LC-BASED METABONOMICS: METHODS AND RESULTS I. Wilson (AstraZeneca, Mereside, UK) |
| 10.10 - 10.40 | Key note lecture 2 HIGH THROUGHPUT AND HIGH RESOLUTION IN UHPLC-MS J-L. Veuthey, S. Rudaz, D. Guillarme (University of Geneva, University of Lausanne, Switzerland) |
| 10.40 - 11.40 | Poster session 1 including coffee break download info |
11.40 - 13.00 11.40 - 12.00 12.00 - 12.20 12.20 - 12.40 12.40 - 13.00 |
Chairman: I. Wilson (UK) Oral communications 1-4 NEW CHIRAL STATIONARY PHASES FOR ENANTIOSEPARATIONS OF CHIRAL DRUGS IN NANO LIQUID CHROMATOGRAPHY AND CAPILLARY ELECTROCHROMATOGRAPHY (OC1) B. Chankvetadze (Tbilisi State University, Georgia) APPLICATION OF SILICA-BASED MONOLITHS FOR PURITY CONTROL OF ANTIBIOTICS (OC2) E. Adams, J. Hoogmartens (Catholic University of Leuven, Belgium) A RAPID AND SENSITIVE CAPILLARY ELECTROPHORESIS METHOD WITH FIELD-AMPLIFIED SAMPLE INJECTION AND IN-CAPILLARY DERIVATIZATION FOR METABOLISM STUDY OF SELENOMETHIONINE BY FLAVIN-CONTAINING MONOOXYGENASES (OC3) X. Hai, E. Adams, J. Hoogmartens, A. Van Schepdael (Catholic University of Leuven, Belgium) QUALITY CONTROL OF PET RADIOPHARMACEUTICALS USING IC WITH ELECTROCHEMICAL DETECTION (OC4) M. Santimaria1, R. Visentin1, G. Bencivenga1, A. Bellini1, C. D’anna1, F. Abballe2, A. Severoni2 (1Unità di Radiofarmacia PET c/o Policlinico “A. Gemelli”, Roma; 2 Dionex S.p.a., S. Donato Milanese, Milano, Italy) |
| 13.00 - 14.30 | Lunch |
14.30 - 15.10 |
Chairman: J. Hoogmartens (Belgium) Plenary lecture 2 PROTEIN CARBONYLS AS A BIOMARKER OF OXIDATIVE STRESS K. Uchida (Nagoya University, Japan) |
| 15.10 - 15.40 | Key note lecture 3 PROTEOMIC ANALYSIS OF POST-TRANSLATIONAL MODIFICATIONS OF HUMAN HISTONES IN CANCER DRUG DISCOVERY M. Naldi, N. Calonghi, L. Masotti, C. Parolin, V. Andrisano (University of Bologna, Italy) |
| 15.40 - 16.00 | Oral communication 5 MOLECULAR MODELLING STUDIES IN THE CHIRAL LIGAND-EXCHANGE CHROMATOGRAPHY OF AMINO ACIDS (OC5) B. Natalini, R. Sardella, A. Macchiarulo, M. Marinozzi, N. Giacchè, R. Pellicciari (University of Perugia, Italy) |
| 16.00 - 17.00 | Poster session I including coffee break download info |
17.00 - 18.00 17.00 - 17.20 17.20 - 17.40 17.40 - 18.00 |
Chairman: H. Lingeman (The Netherlands) Oral communications 6-8 CAPILLARY ELECTROPHORESIS: A POWERFUL TOOL FOR THE ANALYTICAL DEVELOPMENT OF TARGETED ULTRASOUND CONTRAST AGENTS (OC6) S. Cherkaoui (Bracco Research, Geneva, Switzerland) A UNIVERSAL LC-MS APPROACH FOR SMALL MOLECULES: APPLICATION TO THE PROFILING OF FREE FATTY ACIDS IN HUMAN PLASMA (OC7) A. Cappiello, G. Famiglini, P. Palma, V. Termopoli, H. Trufelli (University of Urbino, Italy) BIOASSAY-GUIDED HPLC PURIFICATION TURMERONES FROM TURMERIC OIL OF CURCUMA LONGA (OC8) P.M. Luthra, R. Singh and J. Singh (University of Delhi, India) |
FRIDAY, September 11th
9.00 - 9.40 |
Chairmen: M. Malet-Martino (France), G. Massolini (Italy) Plenary lecture 3 IN VIVO MOLECULAR BIOLUMINESCENCE FUNCTIONAL IMAGING: A NEW POTENT TOOL FOR DRUG DEVELOPMENT AND SCREENING A. Roda (Alma Mater Studiorum University of Bologna, Italy) |
| 9.40 - 10.10 | Key note lecture 4 MS BINDING ASSAYS K.T. Wanner (Ludwig-Maximilians-Universität München, Germany) |
| 10.10 - 10.40 | Key note lecture 5 ANALYTICAL AND CHEMOMETRIC TOOLS FOR BIOMARKER DISCOVERY THROUGH METABOLIC FINGERPRINTING WITH SEPARATION TECHNIQUES C. Barbas1; A. Garcia1; I. Garcia-Perez1; S. Angulo1; J. Teul1,2; M. Ciborowski1,2; M.P. Martinez-Alcazar1; J. Ruperez1 (1Universidad San Pablo-CEU, Boadilla del Monte, Madrid, Spain; 2Medical University of Bialystok, Poland) |
10.40 - 11.40 |
Chairmen: J.L. Veuthey (Switzerland), C. Bertucci (Italy) Poster session II including coffee break download info |
11.40 - 13.20 |
Chairmen: J.L. Veuthey (Switzerland), C. Bertucci (Italy) Oral communications 9-13 |
| 11.40 - 12.00 |
NEW ANALYTICAL STRATEGIES TO PERFORM AUTOMATED PHASE I DRUG METABOLISM STUDIES (OC9) R. Nicoli, R. Curcio, S. Rudaz, J-L. Veuthey (University of Geneva, Switzerland) |
| 12.00 - 12.20 |
ANALYSIS OF NATURAL COMPOUNDS BY INNOVATIVE TECHNIQUES – MEKC AND MONOLITHIC CEC FOR THE DETERMINATION OF NAPHTHOQUINONES IN ELEUTHERINE AMERICANA (OC10) M. Ganzera (University of Innsbruck, Austria) |
| 12.20 - 12.40 |
APPLICATION OF MICRO FABRICATED LC/MS/MS SYSTEM FOR THE QUALITATIVE AND QUANTITATIVE ANALYSIS OF DMPK SAMPLES (OC11) R.S. Plumb1, P.D. Rainville3, I.D. Wilson2 (1Imperial College, London, UK; 2Astra Zeneca, Maccelfield, Cheshire, UK; 3Waters Corporation, Milford, MA, USA) |
| 12.40 - 13.00 |
RECENT ADVANCES IN THE CHROMATOGRAPHIC ANALYSIS OF PHENETHYLAMINE ALKALOIDS IN NATURAL PRODUCTS (OC12) F. Pellati, S. Benvenuti (University of Modena and Reggio Emilia, Italy) |
| 13.00 - 13.20 | IMMUNO-CAPTURE AS ULTIMATE SAMPLE CLEAN-UP IN LC-MS/MS OF BIOMARKERS (OC13) L. Reubsaet, B. Winther, H. Lund, T. Grønhaug Halvorsen (University of Oslo, Norway) |
| 13.20 - 14.30 | Lunch |
14.30 - 15.00 |
Chairman: I.W. Wainer (U.S.A.), G. Aldini (Italy) Key note lecture 6 SOME ANALYTICAL TECHNIQUES TO DETECT COUNTERFEIT DRUGS M. Malet-Martino (Université Paul Sabatier, Toulouse, France) |
| 15.00 - 15.30 | Key note lecture 7 CHARACTERIZATION OF IN VITRO DRUG RELEASE D. Franchi (GlaxoSmithKline S.p.A., Verona, Italy) |
| 15.30 - 15.50 | Oral communication 14 MICELLAR CHROMATOGRAPHIC PARTITION COEFFICIENTS – AN ALTERNATIVE TO TRADITION (OC15) L. Waters (University of Huddersfield,UK) |
| 15.50 - 16.50 | Poster session II including coffee break download info |
16.50 - 18.10 |
Chairmen: K.T. Wanner (Germany), M. Carini (Italy) Oral communications 15-18 |
| 16.50 - 17.10 |
IMMOBILIZED MEMBRANE BASED AFFINITY CHROMATOGRAPHY FOR STUDYING ABC TRANSPORTER-DRUG INTERACTIONS (OC14) P.A. Bhatia, R. Moaddel and I.W. Wainer (National Institute on Aging, National Institutes of Health, Baltimore, USA) |
| 17.10 - 17.30 |
IMPROVED CURCUMIN PLASMA LEVELS AFTER ADMINISTRATION IN HEALTHY VOLUNTEERS OF MERIVA (OC16) P. Morazzoni1, A Riva1, D. Savio2, S. Pengo2 (1Indena S.p.A, Milan, Italy; 2R&D Labs, Saronno, Italy) |
| 17.30 - 17.50 |
PROTEOMIC ANALYSIS OF ENDOTHELIAL CELL SECRETOME: A TOOL FOR THE STUDY OF THE PLEIOTROPIC EFFECTS OF STATINS (OC17) C. Banfi1, M. Brioschi1, S. Barcella1, E. Tremoli1,2 (1Centro Cardiologico Monzino, I.R.C.C.S, 2University of Milan, Italy) |
| 17.50 - 18.10 | HPLC ANALYSIS OF RISPERIDONE AND FEXOFENADINE FOR TDM PURPOSES: PRELIMINARY RESULTS WITHIN A MULTIDISCIPLINARY STUDY ON P-GLYCOPROTEIN (P-gp) ACTIVITY (OC18) L. Mercolini1, L. Albers2, M.A. Raggi1, D. Gripeos3, C. Reist3 (1University of Bologna, Italy; 2Veterans Affairs Medical Center, Mental Health Care, Long Beach, USA; 3Veterans Affairs Medical Center, Research and Development, Long Beach, USA) |
| 20.30 | Gala dinner |
SATURDAY, September 12th
9.00 - 9.30 |
Chairmen: V. Andrisano (Italy), P.G. Righetti (Italy) Key note lecture 8 STUDYING PROTEIN PHOSPHORYLATION BY LC-MS: APPLICATION TO AMNIOTIC FLUID G. Massolinia, C. Temporinia, L. Dolcinib, R. Nicolic, E. Calleria, M. Gallianob, J.-L. Veutheyc, S. Rudazc, L. Ragazzonid, G. Aldinid (a,b University of Pavia, Italy; cUniversity of Geneva, University of Lausanne, Switzerland; d University of Milan, Italy) |
| 9.30 - 10.00 | Key note lecture 9 SELECTIVE (ON-LINE) SAMPLE PREPARATION FOR LC-MS ANALYSIS OF BIOLOGICALLY ACTIVE COMPOUNDS H. Lingeman (University of Amsterdam, The Netherlands) |
| 10.00 - 11.00 | Oral communications 19-21 |
| 10.00 - 10.20 |
SPECIATION OF ARSENIC SPECIES IN URINE FOLLOWING INTRAVENOUS ADMINISTRATION OF ARSTHINOL IN MICE (OC19) I. Ajana1, A. Astier2, S. Gibaud1 (1Nancy Université, France; 2Hôpital Henri Mondor (APHP), Créteil, France) |
| 10.20 - 10.40 |
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP (QSAR) DETERMINATION OF DISTINGUISHING MOLECULAR DESCRIPTORS FOR THE SELECTIVE ESTROGEN RECEPTOR BINDING OF PESTICIDES (OC20) S. Agatonovic-Kustrin and M. Alexander (School of Pharmacy and Applied Sciences La Trobe, University Bendigo, Australia) |
| 10.40 - 11.00 |
EFFECT OF LANTHANUM AND GADOLINIUM ON BIOSYNTHETIC ABILITIES OF REYNOUTRIA JAPONICA IN VITRO CULTURE (OC21) V. Kohoutkova1, P. Babula1, R. Opatrilova1, O. Vrana2, V. Adam3, J. Zehnalek3, R. Kizek3 (1University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic; 2Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic; 3Mendel University of Agriculture and Forestry, Brno, Czech Republic) |
| 11.00 - 11.30 | Coffee break |
11.30 - 12.00 |
Chairmen: R. Maffei Facino (Italy), S. Pinzauti (Italy) |
| 12.00 - 13.00 |
Oral communications 22-24 |
| 12.00 - 12.20 |
A PRECURSOR ION SCAN APPROACH IN LIQUID CHROMATOGRAPHY-ELECTROSPRAY-TANDEM MASS SPECTROMETRY TO DETECT CORTICOSTEROIDS AND THEIR METABOLITES IN HUMAN URINE (OC22) A. Panusa1, M. Orioli1, G. Aldini1, A. Giombini2, C. Tranquilli2, M. Carini1 (1University of Milan, Italy; 2Istituto di Medicina e Scienza dello Sport, Rome, Italy) |
| 12.20 - 12.40 |
FURTHER DEVELOPMENT OF LACTOFERRIN IMMUNOSENSOR (OC23) M. Tomassetti, E. Martini, L. Campanella (University “La Sapienza”, Roma, Italy) |
| 12.40 - 13.00 | INTEGRATED STRATEGIES FOR AFFINITY-BASED SCREENING: FROM BINDING TO IN SILICO STUDIES (OC24) L. Regazzoni1, R. Colombo2, L. Bertoletti2, G. Vistoli1, M. Carini1, R. Maffei Facino1, G. Caccialanza2, G. Aldini1, E. De Lorenzi2 (1University of Milan, Italy; 2 University of Pavia, Italy) |
| 13.00 - 13.30 | Closing Lecture PLUCKING, PILLAGING AND PLUNDERING PROTEOMES WITH COMBINATORIAL PEPTIDE LIGAND LIBRARIES P.G. Righetti, E. Boschetti (Politecnico di Milano, Italy and CEA-Saclay-DSV, iBiTec-S, Gif-sur-Yvette, France) |
| 13.30 - 13.40 | Closing Remarks |
| 13.40 - 14.40 | Farewell Drink |